Publicaciones

Publicaciones relevantes de grupo:

• Intergenerational transmission of the positive effects of physical exercise on brain and cognition.
  McGreevy KR, Tezanos P, Ferreiro-Villar I, Pallé A, Moreno-Serrano M, Esteve-Codina A, Lamas-Toranzo I, Bermejo-Álvarez P, Fernández-Punzano J, Martín-Montalvo A, Montalbán R, Ferrón SR, Radford EJ, Fontán-Lozano Á, Trejo JL.
  Proc Natl Acad Sci U S A. 2019 May 14;116(20):10103-10112.
  PMID: 31010925
  

• Social dominance differentially alters gene expression in the medial prefrontal cortex without affecting adult hippocampal neurogenesis or stress and anxiety-like behavior.
  Pallé A, Zorzo C, Luskey VE, McGreevy KR, Fernández S, Trejo JL.
  FASEB J. 2019 Jun;33(6):6995-7008.
  PMID: 30857420.
  

• The GSK-3-inhibitor VP2.51 produces antidepressant effects associated with adult hippocampal neurogenesis.
  Pérez-Domper P, Palomo V, Gradari S, Gil C, de Ceballos ML, Martínez A, Trejo JL.
  Neuropharmacology. 2017 Apr;116:174-187.
  PMID: 28012947.
  

• Can Exercise Make You Smarter, Happier, and Have More Neurons? A Hormetic Perspective.
  Gradari S, Pallé A, McGreevy KR, Fontán-Lozano Á, Trejo JL.
  Front Neurosci 2016 Mar; 10:93.
  PMID: 27013955.
  

• The relationship between behavior acquisition and persistence abilities: Involvement of adult hippocampal neurogenesis.
  Gradari S, Pérez-Domper P, Butler RG, Martínez-Cué C, de Polavieja GG, Trejo JL.
  Hippocampus 2016 Jul; 26(7):857-74.
  PMID: 26788800.
  

• The postnatal origin of adult neural stem cells and the effects of glucocorticoids on their genesis.
  Ortega-Martínez S, Trejo JL.
  Behav Brain Res. 2015; 279:166-76.
  PMID: 25446750.
  

• The growth factors cascade and the dendrito-/synapto-genesis versus cell survival in adult hippocampal neurogenesis: the chicken or the egg.
  Pérez-Domper P, Gradari S, Trejo JL
  Ageing Res Rev. 2013 Jun;12(3):777-85.
  PMID: 23777808.
  

• Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.
  Martínez-Cué C, Martínez P, Rueda N, Vidal R, García S, Vidal V, Corrales A, Montero JA, Pazos Á, Flórez J, Gasser R, Thomas AW, Honer M, Knoflach F, Trejo JL, Wettstein JG, Hernández MC J Neurosci. 2013 Feb 27;33(9):3953-66.
  PMID: 23447605.
  

• Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice.
  Nishijima T, Llorens-Martín M, Tejeda GS, Inoue K, Yamamura Y, Soya H, Trejo JL, Torres-Alemán I
  Behav Brain Res. 2013 May 15;245:34-41
  PMID: 23428744.
  

• Mifepristone prevents stress-induced apoptosis in newborn neurons and increases AMPA receptor expression in the dentate gyrus of C57/BL6 mice.
  Llorens-Martín M, Trejo JL
  PLoS One. 2011;6(11):e28376.
  PubMed PMID: 22140582.
  

• Antidepressant and proneurogenic influence of environmental enrichment in mice: protective effects vs recovery.
  Llorens-Martín M, Tejeda GS, Trejo JL
  Neuropsychopharmacology. 2011 Nov;36(12):2460-8.
  PubMed PMID: 21796111.
  

• Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis.
  Llorens-Martín M, Tejeda GS, Trejo JL.
  PLoS One. 2010 Aug 16;5(8):e12188.
  PMID: 20808440
  

• Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour.
  Llorens-Martín M, Torres-Alemán I, Trejo JL.
  Mol Cell Neurosci. 2010 Jun;44(2):109-17.
  PMID: 20206269
  

• Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus.
  Glasper ER, Llorens-Martin MV, Leuner B, Gould E, Trejo JL.
  Hippocampus. 2010 Jun;20(6):706-12.
  PMID: 19603528
  

• Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis.
  Llorens-Martín M, Torres-Alemán I, Trejo JL.
  Neuroscientist. 2009 Apr;15(2):134-48..
  PMID: 19307421
  

• The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis.
  Molecular & Cellular Neuroscience. 2008 Feb;37(2):402-11. Trejo JL, Llorens-Martín MV, Torres-Alemán I.
  Central act
  

• Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects.
  Molecular Psychiatry. 2007 Dec;12(12):1118-28. Trejo JL, Piriz J, Llorens-Martin MV, Fernandez AM, Bolós M, LeRoith D, Nuñez A, Torres-Aleman I.
  

• Serum insulin-like growth factor I regulates brain amyloid-beta levels.
  Nature Medicine. 2002; 8(12):1390-7. Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I.
  

• Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation.
  Development. 2001; 128(9):1481-92. Trejo JL, Pons S, Martínez-Morales JR, Martí E.
  

• Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.
  Journal of Neuroscience. 2001; 21(5):1628-34. Trejo JL, Carro E, Torres-Aleman I.