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Research Departments >Functional and Systems Neurobiology department > Neuroactive steroids> Publications

Research Report Personnel Publications Other

Representative publications (2015-2020)

  • Crespo-Castrillo A, Garcia-Segura LM, Arevalo MA (2020) The synthetic steroid tibolone exerts sex-specific regulation of astrocyte phagocytosis under basal conditions and after an inflammatory challenge. J of Neuroinflammation, doi: 10.1186/s12974-020-1719-6.

  • Acaz-Fonseca E, Ortiz-Rodriguez A, Azcoitia I, Garcia-Segura LM, Arevalo MA (2019) Notch signaling in astrocytes mediates their morphological response to an inflammatory challenge. Cell Death Discov, 5:85. doi: 10.1038/s41420-019-0166-6.

  • Ortiz-Rodriguez A, Acaz-Fonseca E, Boya P, Arevalo MA, Garcia-Segura LM (2019) Lipotoxic Effects of Palmitic Acid on Astrocytes Are Associated with Autophagy Impairment. Mol Neurobiol, 56(3):1665-1680. doi: 10.1007/s12035-018-1183-9.

  • Crespo-Castrillo A, Yanguas-Casás N, Arevalo MA, Azcoitia I, Barreto GE, Garcia-Segura LM (2018) The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury. Mol Neurobiol, 55(11):8651-8667. doi: 10.1007/s12035-018-1008-x.

  • Yanguas-Casás N, Crespo-Castrillo A, de Ceballos ML, Chowen JA, Azcoitia I, Arevalo MA, Garcia-Segura LM (2018). Sex differences in the phagocytic and migratory activity of microglia and their impairment by palmitic acid. Glia, 66(3):522-537. doi: 10.1002/glia.23263.

  • Ruiz-Palmero I, Ortiz-Rodriguez A, Melcangi RC, Caruso D, Garcia-Segura LM, Rune GM, Arevalo MA (2016). Oestradiol synthesized by female neurons generates sex differences in neuritogenesis. Sci Rep, 6:31891. doi: 10.1038/srep31891.

  • Acaz-Fonseca E, Duran JC, Carrero P, Garcia-Segura LM, Arevalo MA (2015). Sex differences in glia reactivity after cortical brain injury. Glia, 63(11):1966–1981. doi: 10.1002/glia.22867.

  • Arevalo MA, Azcoitia I, Garcia-Segura LM (2015). The neuroprotective actions of oestradiol and oestrogen receptors. Nat Rev Neurosci, 16(1):17-29. doi: 10.1038/nrn3856.


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